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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNKS2
All Species:
41.52
Human Site:
S454
Identified Species:
76.11
UniProt:
Q9H2K2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2K2
NP_079511.1
1166
126918
S454
Q
T
C
R
L
L
L
S
Y
G
C
D
P
N
I
Chimpanzee
Pan troglodytes
XP_001137443
1327
142033
S612
Q
T
C
R
L
L
L
S
Y
G
S
D
P
S
I
Rhesus Macaque
Macaca mulatta
XP_001090358
1327
142132
S612
Q
T
C
R
L
L
L
S
Y
G
S
D
P
S
I
Dog
Lupus familis
XP_534962
1316
141794
S604
Q
T
C
R
L
L
L
S
Y
G
C
D
P
N
I
Cat
Felis silvestris
Mouse
Mus musculus
NP_001157107
1166
126725
S454
Q
T
C
R
L
L
L
S
Y
G
C
D
P
N
I
Rat
Rattus norvegicus
NP_001101077
1166
126761
S454
Q
T
C
R
L
L
L
S
Y
G
C
D
P
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508887
1320
142724
S605
Q
T
C
R
L
L
L
S
Y
G
S
D
P
S
I
Chicken
Gallus gallus
Q5F478
990
107379
L343
D
K
D
G
N
T
P
L
H
V
A
A
R
Y
G
Frog
Xenopus laevis
NP_001088420
1303
140252
S588
Q
T
C
R
L
L
L
S
F
G
S
D
A
S
I
Zebra Danio
Brachydanio rerio
Q502K3
1071
114412
S384
H
L
A
V
L
Y
G
S
S
D
C
C
R
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651410
1181
127927
S451
Q
A
V
R
L
L
L
S
Y
A
A
D
T
N
I
Honey Bee
Apis mellifera
XP_396483
1166
127309
S452
Q
A
C
R
I
L
L
S
Y
N
V
D
P
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186587
1157
126547
S454
E
A
C
K
L
L
L
S
Y
G
A
D
T
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.5
72.5
87.9
N.A.
97.2
97.2
N.A.
72.5
24
73.1
23.3
N.A.
65.3
70.6
N.A.
69.5
Protein Similarity:
100
80.3
80.3
88.2
N.A.
98.8
99
N.A.
80.5
40.3
81.3
38.9
N.A.
79.8
83
N.A.
83.1
P-Site Identity:
100
86.6
86.6
100
N.A.
100
100
N.A.
86.6
0
73.3
20
N.A.
66.6
66.6
N.A.
53.3
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
100
N.A.
93.3
6.6
86.6
26.6
N.A.
66.6
80
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
8
0
0
0
0
0
0
8
24
8
8
0
8
% A
% Cys:
0
0
77
0
0
0
0
0
0
0
39
8
0
0
0
% C
% Asp:
8
0
8
0
0
0
0
0
0
8
0
85
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
8
0
0
70
0
0
0
0
8
% G
% His:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
77
% I
% Lys:
0
8
0
8
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
0
8
0
0
85
85
85
8
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
8
0
0
0
39
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
62
0
0
% P
% Gln:
77
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
77
0
0
0
0
0
0
0
0
16
0
0
% R
% Ser:
0
0
0
0
0
0
0
93
8
0
31
0
0
47
0
% S
% Thr:
0
62
0
0
0
8
0
0
0
0
0
0
16
0
0
% T
% Val:
0
0
8
8
0
0
0
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
77
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _